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Sakura's design had gone through several different changes during it's development. Among those scrapped concepts include a Motion Capture actress and a Mountain Climbing Guide.
Contributed by ZpaceJ0ck0
The interaction between Abigail and Juri during the former's characters story varies between regions.

On the Japanese version, Juri mistakes Abigail's onomatopoeic sounds of a car engine for the word ブス (busu; "ugly"). Because the pun has no meaning in English, this line of dialogue was changed to Abigail talking about feeling like a flat tire, only so that Juri would overhear this and confuse it with her being called flat.
Contributed by ZpaceJ0ck0
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Menat's design had gone through several different changes during it's development. Among those scrapped concepts include being a "Pizza Assassin" whose personality and mannerims were based on B.B Hood/Bulleta from the Darkstalkers series, a delinquent named Rita and a magician; during this stage of development she was meant to be an Italian like Rose. Later on she was considered to use other objects to attack, including smoke, golden dust, and being a tahtib fighter that uses a staff; this is the stage in which Capcom settled for Menat to be an Egyptian.
Contributed by ZpaceJ0ck0
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The 13th color scheme for Menat's battle costume is based upon a similar costume wore by Milla Jovovich's character Leelo in the 1997 film The Fifth Element.
Contributed by ZpaceJ0ck0
M.Bison has an unused teleport move that he could use on V-Trigger, allowing him to transport him behind, in front of, or above the opponent. The move was removed in the final release because it was deemed too strong, with the only remnants being found in the game files.
Contributed by ZpaceJ0ck0
There were several concepts for new characters that didn't make it out into the final game. One example of this is a character with a Soccer/Football based style, but it was cut because the idea was too similar to that of Roberto Miura from the Rival School series (also developed by Capcom). Another example of a character that was cut completely is a "Fighting President", which was an idea that also came up during the development of Street Fighter IV.
Contributed by ZpaceJ0ck0
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Guile's V-Skill was originally allowed the player enter a crouched, fully charged state that could cancel any move. It was removed because the move was incredibily strong.
Contributed by ZpaceJ0ck0
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Charlie Nash's V-Skill consisted of him perfoming a high-speed dash on the ground or in the air. It was cut because it overlapped with the image of the Sonic Move V-Trigger teleport, as well as not being considered that interesting of an idea by the developers.
Contributed by ZpaceJ0ck0
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Zangief's V-Skill was originally going to be a move called “Grab Anything”, which would have allowed the Russian Brawler to activate a grab from any normal attack on the ground or in the air. It was cut because the move was considered too strong.
Contributed by ZpaceJ0ck0
Dhalsim's V-Skill originally consisted of him forcibly switching positions with the opponent, making it effective against projectile characters.

This move wasn't as good as the developers originally envisioned, and it proved frustrating for players, so this move wasn't included in the released game.
Contributed by ZpaceJ0ck0
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Vega's original V-Trigger consisted of Vega calling down a steel cage that he could climb up and attack from in a similar vein to his stage in Street Fighter II and Street Fighter Alpha 3. It was never implemented, because the cost of implementing the move would be too high.
Contributed by ZpaceJ0ck0
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Zeku's design had gone through several different changes during it's development. Among those scrapped concepts include a demon slayer and a fighter who is ''skilled at picking up random items and turning them into make-shift weapons''.
Contributed by ZpaceJ0ck0
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Early concept art originally depicted Necalli as a Sasquatch-like creature.
Contributed by ZpaceJ0ck0
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Concept artwork shows that Rashid nearly resembled a cyborg, with a orange and yellow belt and some sort of dispenser on his left arm.
Contributed by ZpaceJ0ck0
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The earliest design of Laura bore a near resemblance to Street Fighter EX fighter Pullum Purna, a later design had her more closely resembling her brother Sean.
Contributed by ZpaceJ0ck0
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Birdie's early design in the game was nearly identical to his original appearance in the original Street Fighter game, being portrayed as a tall, muscular white/light-skinned man with a normal blonde mohawk.
Contributed by ZpaceJ0ck0
On April 25th 2017, the Temple Hideout stage was removed as it featured a Muslim prayer voice sample from an audio collection known as "Voice Spectral: Volume one", which some argued did not fit the stage, a Buddhist temple. Capcom decided to temporarily remove the stage and publish it again on May 31st 2017 with a different theme.
Contributed by ZpaceJ0ck0
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Early concept art for F.A.N.G had originally depicted him as a Shaolin Monk.
Contributed by ZpaceJ0ck0
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The CPT costumes from 2016 and 2017 were inspired by old promotional artwork by artist Kinu Nishimura.
Contributed by ZpaceJ0ck0
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A character based on Momotaru from Capcom's puzzle game Pirate Ship Higemaru was considered as a playable character for the game. Birdie was chosen over him in the end, however. Momotaru was instead given a profile in the Street Fighter V character guide in August 2016.
Contributed by ZpaceJ0ck0
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The characters Cody, Guy, Mike Haggar, and Maki from the Final Fight series make a cameo in the "Union Station" background in a banner on the top left of the stage. Additionally, Eisbahn, a character from the rhythm battle RPG game Otoranger (also developed by Capcom) makes a cameo as well on a banner seen on the left of the stage.
Contributed by ZpaceJ0ck0
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Tiffany Lords makes a background cameo in the downloadable Kanzuki Family Private Beach stage along with Hinata Wakaba.
Contributed by ZpaceJ0ck0
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It's possible to access Urien's Street Fighter III costume in game. During the loading screen, holding LP, MK, and HP will alter his intro animation to him burning off his current costume, revealing his classic costume.
Contributed by SOGESNAKE
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Several stage elements as well entire stages themselves were cut completely from the final game. For example, Mike Haggar from the Final Fight series was going to appear on Karin's stage via an elevator that would automatically go up and down, but was cut for being "too random". An example of a stage being cut completely was a military base that contained huge robots and aliens, which was removed for having little to no relation with the storyline.
Contributed by ZpaceJ0ck0
The game's E3 demo and initial release had a glitch on the character select screen. If the second player chose a female character, their breasts would bounce excessively. Capcom later released a patch to correct the bug.
Contributed by ProtoSnake
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The game originally had a more realistic look during it's early stages of development.
Contributed by ZpaceJ0ck0
The creation of newcomer Rashid was a close collaboration between Capcom Japan, Sony, and Capcom's Middle Eastern distributor Pluto Games. Katsuhiro Harada, the producer of rival fighting game series Tekken, also encouraged Yoshinori Ono to include a Middle Eastern fighter in the Street Fighter main games.
Contributed by ZpaceJ0ck0
The idea of a fighter who uses poison in the Street Fighter games was originally considered during the development of Street Fighter III: 3rd Strike, when the team members had a debate on including Remy (a character with a playstyle similar to Guile's) or a different, poison-using character.

Capcom eventually decided to implement this idea with the SFV newcomer, F.A.N.G.
Contributed by ZpaceJ0ck0
The game was unofficially revealed through a YouTube video on December 5, 2014, which was promptly taken down. It was officially revealed the next day during the 2014 PlayStation Experience in Las Vegas and was announced as being developed exclusively for the PlayStation 4 and Microsoft Windows.
Contributed by DrakeVagabond