When you encounter Cody Travers and Guy in Bryan Fury and JACK-X's story mode, Bryan asks JACK-X how strong their opponents are. Jack-X claims their power levels are over 9,000. This is a reference to a infamous meme from the "Ocean Dub" version of the Dragon Ball anime.

The Japanese version doesn't feature this joke.
Contributed by ProtoSnake
When you encounter Steve Fox and Hwoarang in Hugo and Poison's story mode in the Japanese dub, Hugo says "I am number one!" while clearly pointing to himself. This was replaced with "We are number one!" in the English dub.
Contributed by ProtoSnake
When talking about his working relationship with Yoshinori Ono, Katsuhiro Harada stated that he is someone who, "just kind of comes and goes as he pleases, and makes his own desk."
Contributed by Stryker94