Creating a fresh save file of Devil May Cry on a PlayStation 2 memory card and going to the memory card menu of the PlayStation 2 console will display the data as a "chibi" 3D model of Trish. Attempting to delete the save file will cause Trish to put her hand on her forehead and shakes her head in disappointment. Attempting to copy the file will cause her to pump one arm in the air in excitement, and during the copy process, she will start dancing.
In the opening scene, bottles of Jack Daniel's can be seen on Dante's desk.
Dante used the name Tony Redgrave as an alias in his early days of demon slaying. When asked about the name, director Hideki Kamiya stated that "Antonio Redgrave was a journalist that Dante respected, so he used it as his fake name during his days as a mercenary..." In Bayonetta, Luka's father, Antonio Redgrave, was a world famous journalist that documented supernatural events, people, and places. It's very likely that the two Tonys may be the same person.
Devil May Cry started out as Resident Evil 4. Producer Shinji Mikami felt it strayed too far from the series' survival horror roots and gradually convinced all the staff members to make it an independent game. The story was eventually rewrote to be set in a world full of demons and the hero's name was changed to Dante.