Sardius, the final boss, was named Samael in The Japanese version. In Hebrew, Samael means "venom of God" or "poison of God". In Jewish lore, Samael is the archangel of death. The name change may be due to Nintendo's anti-religious reference policy.
Contributed by Kakariko Kid
The crosses in the first level of the game were changed to ankhs outside of Japan.
Contributed by ProtoSnake