Platform: Game Boy

Popular conceptions about Nintendo's release history in Europe claim that their hardware was never released in the former Eastern Bloc until the 21st century. Rather, these countries instead saw the proliferation of various clone consoles called "Famiclones", such as the Dendy (a Taiwanese-built bootleg that achieved widespread popularity in the Commonwealth of Independent States, made up of the ex-republics of the former Soviet Union) and the Pegasus (which became as popular in Poland as the Dendy did in Eastern Europe). However, while Famiclones did indeed dominate the Eastern European gaming market during the 1990s, Nintendo was not only aware of this, but actively attempted to halt the spread of bootlegs in these regions in favor of officially sanctioned products.

In 1994, Nintendo made a deal with Steepler, the Dendy's distributor in Eastern Europe, to permit continued sale of the Dendy in exchange for equal distribution of the Super Nintendo Entertainment System and Game Boy in the Commonwealth of Independent States; official Russian releases of these systems even included Dendy stickers on the packaging to reflect the arrangement. Meanwhile, in various other parts of the former Eastern Bloc, Nintendo made deals with other third-party distributors; among others, the NES, SNES, and Game Boy saw official releases in Poland, Hungary, and the former territories of Yugoslavia and Czechoslovakia during 1993–1994.

Due to South Korea banning Japanese cultural imports at the end of World War II, the Nintendo Game Boy was distributed by South Korean company Hyundai, and was named the Mini Comboy.

After the second phase of the Gulf War ended in early 1991, Dr. Stephan Scoggins, a medic during the war, mailed his Game Boy to Nintendo of America hoping to get a replacement after it was damaged when his tent burned down in a fire. While the back of the console was in fair condition, the front was melted, severely charred and blistered, and the technicians that received it initially determined it could not be fixed. As an experiment, they inserted a copy of Tetris and powered it on, and to their surprise, the console still worked. The D-Pad, A and B buttons were nonfunctional, but the Start and Select buttons worked as normal. The magazine Nintendo Power sent Scoggins a replacement Game Boy "as a special 'Desert Storm' courtesy", and his letter asking for a replacement along with pictures of the console were featured in the magazine's July 1991 issue. The damaged Game Boy was not discarded; it was later displayed at the Nintendo New York store in New York City since its opening in 2001. As a testament to the console's durability and longevity, it remained powered on, looping the title screen and attract mode demo of Tetris, and receiving timely maintenance for over 20 years, until it was returned to Nintendo of America's headquarters in Redmond, Washington in 2023.

Turning on the Game Boy Printer while holding the Feed Button will print a test image of Mario saying "Hello!"

Lionel Simmons missed two games for the Sacramento Kings in his 1991 NBA rookie season due to tendinitis in his wrist and forearm from playing the Game Boy too much.

The Game Boy "Controller Kensa" cartridge is a test cart that allowed Nintendo Service Representatives to check the buttons on a Game Boy (or a SNES controller if it is in a Super Game Boy). This cart has unused test music and unused graphics from the games Alleyway and Super Mario Land.

In 2018, rapper Soulja Boy attempted to sell his own line of video game consoles, called the SouljaGame line, sold for $149.99 for a console and $99.99 for a handheld. Advertising claimed that the consoles would be compatible with a variety of consoles' games, including modern platforms like the PlayStation Vita, Nintendo 3DS, and Nintendo Switch. They obviously did not have such compatibility, and were rather a generic retro emulator console one could find on small business-oriented retail websites such as Wish and AliExpress loaded with pirated and modified games sold at a markup. Game libraries featured included the Neo Geo, NES, SNES, Game Boy, Game Boy Color, Game Boy Advance, Sega Genesis, Sega Master System, Sega Game Gear, and PlayStation. The only difference from these pre-existing consoles is a photograph of Soulja Boy printed onto the box. He would eventually stop selling SouljaGame consoles, with the website for the console redirecting to Nintendo's 3DS website.