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In a 2013 interview with Polygon, director Bryce Holliday revealed that Luigi's portrayal in the game was influenced by the 1990 British comedy series Mr. Bean. The show served as reference material for Luigi's animations and characterization, with Holliday noting parallels between Luigi and the show's title character as a "hapless fool and reluctant hero." Holliday also felt that these similarities would help audiences sympathize with Luigi, which in turn would supplement the comic relief that his reactions and mishaps provide.
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When starting a mission in Gloomy Manor, there is a chance that Luigi will be teleported into the mansion landing on the Poltergust rather than on his rear.
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During an interview the game producers said that the mission where the player leads Toad out of the Mansion was inspired by leading Zelda out of the Castle in The Legend of Zelda: A Link to the Past.
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"Rumor has it that this Greenie comes from the middle ages, where he was a knight searching for the kidnapped princess. Sadly, wherever he went, she always seemed to be in another castle"
The last bit is obviously a nod to Super Mario Bros. on the NES, where Princess Peach was always in another castle.
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While Luigi normally calls out "Hello" or "Yoohoo" when the + Control Pad is used, in the later missions in the Treacherous Mansion, and after finishing the game, he will instead call out "Mario" as a reference to the original Luigi's Mansion.
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In the French translation, the first letter of each bonus mission in order reads "Luigi".
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The First edition of Luigi's Mansion 2 released in Europe received glow in the dark covers.
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There is a cutscene in Treacherous Mansions in which two Strong Greenies bring a suit of armor to life. This is a reference to the film "Frankenstein".
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The scene in the Hollow Tree level, in which Luigi looks down the staircase, is a reference to a movie called "Vertigo" and the camera effect named after it.
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The music which is played in the elevator is the same tune which is heard at the pause screen in Mario Strikers Charged, a previous Mario game which was also developed by Next Level Games.
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The opening scene in which Luigi is sleeping in front of a TV which suddenly displays static, awakening him and causing him to reach out towards it, is a reference to the 1982 film "Poltergeist".
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At the beginning of the game, if you look beyond Luigi, you can find the map from the beginning of the first game.
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The first letter of each of the five possessor's (boss ghosts) names spell out the word GHOST.
Grouchy Possessor
Harsh Possessor
Overset Possessor
Shrewd Possessor
Tough Possessor
Grouchy Possessor
Harsh Possessor
Overset Possessor
Shrewd Possessor
Tough Possessor
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The first letters from the names of the five playable mansions spell out the word GHOST.
Gloomy Manor
Haunted Towers
Old Clockworks
Secret Mine
Treacherous Mansion
Gloomy Manor
Haunted Towers
Old Clockworks
Secret Mine
Treacherous Mansion
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