In Nuketown 2025 there are books that read "Edward Richtofen", a character from the original Black Ops.

When using Tactical Insertions in Multiplayer, a set of numbers will appear on the small screen of the device. These numbers change for each map and are actually real-life geographic locations and, via Google Maps, are shown to lead to places that highly resemble the map they're displayed on. Two notable examples of this are the maps "Hijacked", which leads to a ship off of the cost of an island, and "Express", which leads to a train station in Los Angeles.

An unused camo called "Massacre" can be found in the game's files. It looks similar to the red camo from Call of Duty: Black Ops, but it's darker.

There are two scrapped multiplayer maps that can be found within the game's files. The first is Promenade, which seems to be an early version of Plaza. The other scrapped map is an early version of Standoff.

There is a label on the back of the Guardian that reads "1.21 GW". This is a reference to the Back to the Future movies, where 1.21 Gigawatts are required to activate the DeLorean time machine.

When the Mystery Box is not active in the Zombies game mode, a teddy bear will be left in its place. Every so often, the bear will move its head, as though assessing the area, and then return to its original position.

The Predator reticle for the Reflex Sight was inspired by the Predator's laser sight from the Predator films.

There was a mode cut from the game called "Hacker". The objective would have been to disable and hack neutral A.G.R.s (Autonomous Ground Robots). Points would be earned both for hacking the A.G.R.s and killing other players, with using the A.G.R.s to kill other players rewarding the most points. The only thing that remains of this game mode, however, is a cut menu icon.

In the PlayStation 3 release, placeholder text scripted as "MENU_DLC5_MAPS" can be found in the game's code, hinting that Treyarch may have considered releasing 5 DLCs instead of the final 4.

In patch 1.12, the Ray Gun Mark II was unintentionally added to every zombie map before the DLC Vengeance came out for Xbox 360. It was later removed with a hotfix a few weeks later.

Near the end of the Nuketown Zombies trailer, one of the CDC characters can be heard talking, but in the actual map none of the 4 characters have any quotes.

Upon entering 115 into the number pad in Mob of the Dead, the player will hear "Not this time" or "Maybe next time" and the number will change to 666 referencing the Bible and the number of the beast.

On the DLC map 'Cove' if you look across the water you can see the boat from the map 'Hijacked'.

Inside the trailer in the DLC multplayer map Studio, multiple weapon props can be found. Dual Ray Guns, Sliquifiers and Vektor K10s as well as an unknown weapon.

There is an Atari hidden in Nuketown 2025 with 4 playable games. To accomplish this, you have to shoot the heads off all mannequins in under 2 minutes. Also, while playing, your character's hands will pixel-ate.

In the "Meltdown" map, you can find a pink box of doughnuts by a power console. This is a reference to the Simpsons, as Homer Simpson works in a power plant, and regularly eats pink frosted doughnuts from a pink box.

Unlocking all gold camo's in a weapons class (Such as Assault Rifles) will result in Diamond camo being unlocked for that class.

Throwing a monkey bomb in zombie mode into a lava pool or outside the map will result in the monkey bomb not functioning and a demonic laugh being heard.

On the zombies map Green Run the original zombies map 'Nach Der Untoten' can be found in the cornfield. Only the spawn room can be entered however.

The population counter in Nuketown Zombies counts down for every zombie killed. After every 100 zombies killed, the clock on the map will turn 1 hour. When the population is 11 and the clock is at 5, a Fire Sale power up is present in the garden shed with a power-up in it. Furthermore, every time the clock changes the power-up changes too.