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Pokémon Puzzle League is the first Pokémon game to be released exclusively to the Western market, and not in Japan.
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Hidden inside the code are two unused voice clips. They are presumably from staff issuing a little message to loved ones, as one is in Japanese and reads "Yumi-chan, I love you" and the other reads "I love you Liz."
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In order to temporarily unlock Mewtwo in vs. mode, you must hold Z, and then press B, Up, L, B, A, Start, A, Up, R. The combination spells out "Bulbasaur".
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The version of Panel de Pon included on Nintendo Puzzle Collection was originally intended to be released on the Nintendo 64 in Japan, and a prototype featuring the Panel de Pon fairy characters is known to exist. It did see release on the console in other regions as Pokémon Puzzle League, however.
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Pokémon Picross
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Pokémon Home
Pokémon Colosseum
Pokémon Channel
PokéPark Wii: Pikachu's Adventure
Pokémon Pokopia
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Pokémon Ruby Version
Pokémon Ultra Moon
Pokémon Y
Pokémon Pinball
Pokémon Sun
Pokémon Red Version
Pokémon Sword
Pokémon Brilliant Diamond
Pokémon Platinum Version
Pokémon Blue Version
Pokémon Moon
Pokémon Black Version
Pokémon HeartGold Version
Nintendo Puzzle Collection
Pokémon Picross
Pokémon Scarlet
Pokémon Gold Version
Pokémon Pearl Version
Pokémon Green Version
Pokémon SoulSilver Version
Pokémon Crystal Version
Pokémon Black Version 2
Panel de Pon
Pokémon: Let's Go, Eevee!
Pokémon Legends: Arceus
Pokémon Mystery Dungeon: Blue Rescue Team
Pokémon Silver Version
Panel de Pon
Pocket Monsters Stadium
Pokémon Yellow Version: Special Pikachu Edition
Pokémon Battle Revolution
Pokémon Diamond Version
Pokémon Shield
My Pokémon Ranch
Pokémon Alpha Sapphire
Pokémon Violet
Pokémon Shining Pearl
Pokémon Conquest
Pokkén Tournament
Pokémon White Version 2
Pokémon Emerald Version