After the ending credits, there is a morse code conversation between two unknown people. The first massage says "Vault facility occupied. Project Vulture Sentry System has been disabled. Awaiting instructions." The second is a German sentence, that when translated says "Confirmed. Implementation of phase Two. Activate project ALBATROSS." This was meant to set up for a sequel that (at the time of writing this) has yet to be announced.

In various locations within the game you can see billboards advertising Tricell, a pharmaceutical company from Resident Evil 5.

When you first encounter The Mohole boss fight, Super Joe will normally tell Spencer:


However, there is a chance that Super Joe will instead say something bluer:


The closed captions do not change to accommodate for the dialogue change, making it a surprise. It's not known if there are any pre-requisites to triggering this secret, or if there is just a randomized chance of hearing it, but it can happen if you die to the boss and attempt it again at least once.