The Possession Orb used for Abe's possession ability was added as a solution to handle the ability in a 3D environment. An earlier idea was to have Abe automatically target the closest possessable character the player could see, similar to the earlier Oddworld games, but this was later scrapped.

The Intern's at Vykker's Labs have 5 "fingers", and no thumbs. Their vertical mouths were stitched together completely in order to prevent them from whistling to the sound of their annoying music.

Abe's Mother, Queen Sam, was meant to have a role in the game but due to time constraints, this particular part of the plot was cut.

Munch's Oddysee was originally going to be released for the PlayStation 2, with different level layouts, enemies, cutscenes, and areas, but was scrapped and put on the Xbox.

The idea to move the game to Xbox was based on the development team not only wanting to use a more powerful console, which would allow them to flesh out the world better, but also thinking it would be a better long term plan to publish the games on the console. Microsoft even worked with Oddworld Inhabitants to help make the Xbox better for them to work on it.