One of the challenges in Nickelodeon Kart Racers 3: Slime Speedway is called "that's a good hook!" and allows the player to unlock Dr. Paula Hutchinson as a crew member. Unlike other challenge titles which reference catchphrases and episode titles, this references a well-known behind-the-scenes story from the production of Rocko's Modern Life, where a request from a Nickelodeon executive for the series to feature a strong female role model with a "good hook" lead to the conception of Hutchinson and her signature hook hand.

Nickelodeon All-Star Brawl 2 was the first Nickelodeon product where Korra from The Legend of Korra isn't voiced as an adult by Janet Varney, instead being voiced by Jacqueline Grace Lopez, while Nickelodeon Kart Racers 3: Slime Speedway was the last time Varney portrayed the character. The reason for this is that in 2022, a year before All-Star Brawl 2 was released and the same year as Kart Racers 3, Varney announced that she was stepping down from the role because she wanted Korra to be voiced by a person of color, much as Korra herself is, following the announcement of a new Avatar: The Last Airbender movie starring Korra to be released in 2025.