Choosing the option "Let me show you how to do that" when talking to Emmet in the bar 10 times will trigger a hidden knife mini-game.

Ben's last name is Throttle, but this is never mentioned in the game. His last name was dropped from the final version to avoid potential legal problems with the animated series Biker Mice from Mars, which had a character named Throttle. Ben is referred to as "Ben Whatsisname" in the manual, but his full name can be seen in concept art.

Tim Schafer originally wanted to include a section in the game where Ben would take peyote, and have the player play through a dream sequence in Ben's mind. While this idea was dropped from the game, it formed the inspiration for Tim Schafer later game, Psychonauts.

The hood ornament on the Corley Motors hovercar seen at the beginning of the game is modeled after Tim Schafer, the game's writer, designer, and project leader.

One of the cars that can be found in the junkyard is modeled after a 1969 Pontiac Le Mans, a car that Tim Schafer owned during the development of Full Throttle. When Tim Schafer went out to lunch one day, the engine exploded and the car caught on fire. Later, when Schafer returned to the office, he found that Peter Chan, Lead Artist for Full Throttle, had painted the car into the game.

When the player looks at the car, Ben will say "Fire Damage. Forget about it."