On the bookshelf located in the Fortress of Doom, there is a book titled "How to Comb your Mustache" by Cliffton M. Fischbach, the father of YouTuber Markiplier, who passed away due to lung cancer. The developers included his name as an easter egg in the game because Mark Fischbasch stated that his father got him into the very first game in the series.

When asked by GamesBeat what the word "Eternal" meant in this game, creative director Hugo Martin described the word "Eternal" as an "eternal struggle for the good and evil. It's meant to symbolize that there's always going to be demons and there's always going to be a slayer."