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The mystical weapon Azoth was named by the game's designer Yasuhisa Kawamura as an inside joke, referring to another weapon called Parcelsus' Sword in one of his earlier works, Resident Evil 3: Nemesis. Azoth and Paracelsus both originate from the same mythos.
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Rise of Nightmares was the first game for the Kinect to be given a Mature rating from the Entertainment Software Ratings Board.
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