The breast bouncing animations were toned down in the Playstation version, and the number of times the player can grab characters breasts was limited. According to the Playstation 20th anniversary Famitsu interview, the reason for this was because of a dispute between Hideo Kojima and SIE'S CEO Shuhei Yoshida, the latter believing that the feature was excessive.

The visual designs of the co-protagonists Jonathan Ingram and Ed Brown are based on actors Mel Gibson and Danny Glover's roles as Martin Riggs and Roger Murtaugh from the Lethal Weapon series.