To coincide with the release of the NES Battletoads game in 1991, a Game Boy game titled Battletoads was released later that year. However, this Game Boy game was not a port of the original NES game, and was instead a unique single-player game with different levels. A second Battletoads game for the Game Boy would later release in 1993, called Battletoads in Ragnarok's World, that was more faithful to the original NES game, porting over seven of its levels albeit still being a single-player game.

There are 4 different sets of dialogue that the Black Queen and Professor T. Bird will speak in the ending cutscene. These sets of dialogue are selected at random.

In a few levels, there are enemies that can steal health by grabbing the energy bars from the health meter directly, as opposed to attacking the player's character. According to the game manual, these enemies are called 'Vaders, "survivors of the original invaders", referencing the game Space Invaders.