Much like the previous games, Vesperia also features a Coliseum-based Cameo battle set. This time around the player fights against major antagonists from the series, albeit with them using titles as opposed to their actual names. They are, in order:

• Time Traveler: Dhaos from Tales of Phantasia
• Sorrowful Queen of Darkness: Shizel from Tales of Eternia
• Killer of Heroes: Barbatos Goetia from Tales of Destiny II (much like his home game, using any item during the fight will trigger his Mystic Arte)
• Traitor to Heaven: Kratos Aurion from Tales of Symphonia