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In 2019, amid a rise in popularity for anti-vaccine conspiracy theories and psuedoscience, a petition was started for Plague Inc. to implement anti-vaccine advocates, or "anti-vaxxers", as a situation that would buff your disease. Ndemic Creations, while noting that anti-vaxxers do technically exist as a smaller part of the "Science Denial" scenario along with flat Earth theorists and climate change deniers, agreed to include the movement as a solo buff for the disease, but did not have an idea for how they would work in gameplay at the time. Anti-vaxxers have not yet been added to the game, but a second buff partially referencing anti-vaxxers, "Fake News", would be added.
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In 2016, one of the most popular names used by players for their virus was 'Trump', according to the game's developer, Ndemic Creations. This is a reference to presidential candidate Donald Trump.
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Early in the game, before your infection gets noticed, there is a chance you will receive a message reading, "Pylons 'vital to high-tech society' A new energy report confirmed the need to construct additional pylons in order to ensure a sustainable energy supply in the future"
This is a reference to the Protoss race from Starcraft, who are required to build pylons before they can build more units.
This is a reference to the Protoss race from Starcraft, who are required to build pylons before they can build more units.
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