Persona 4 Arena was the first ever region locked PlayStation 3 game, 6 years after the inital release of the PlayStation 3.
Fuuka Yamagishi's voice actress in Persona 3, Mela Lee, was replaced by Wendee Lee for this game.
Arc System Works wanted Ryoyaro Dojima (Yu's uncle) as a playable character. Instead of a persona, he was supposed to summon his daughter Naniko to his side. This idea was rejected by Atlus.
The color palate switch was meant to make the playable charters look like past Persona characters, Guilty Gear characters or BlazBlue characters.
All of the voice actors returned to reprise their roles except for Tracey Rooney and Dave Wittenberg (Chie and Teddie respectively). They were replaced with the "Persona 4: The Animation" actors, Erin Fitzgerald and Sam Riegel. The new actors returned for "Persona 4 Golden."