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According to executive producer John Hight in an interview with GameSpy, Westwood Studios considered making a sequel to Nox at one point, in addition to the NoxQuest expansion pack which did release. However, this sequel never came to pass before Westwood was shut down and merged into EA Los Angeles in 2003.
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Michael Booth, the game’s creator, envisioned Nox as an updated version of the 1985 Atari game Gauntlet. He also looked at real-time magical combat games such as "Magic: The Gathering" and Mortal Kombat, hence the medical setting for Nox.
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