As revealed in the 2023 Insomniac Games ransomware data leak, Jean Grey was originally planned to be a playable character, using her telepathic abilities to engage in combat for about five missions in the game. Following the leak, Insomniac decided to more closely focus on Wolverine as the only playable character, but would keep her presence for the "team vibe". It has been speculated that the developers grew cold feet about having a second playable character due to the poor reception of Mary Jane's stealth sections in Marvel's Spider-Man and Marvel's Spider-Man 2.

The Spider-Man and Wolverine games developed by Insomniac Games are established to take place in Earth-1048 in Marvel's multiverse. This reality designation was first established in the 2018 comic miniseries "Spider-Geddon", which canonically takes place sometime after the events of the first Spider-Man game.

On December 12, 2023, a ransomware gang named Rhysida announced they they had hacked internal servers at Insomniac Games and stole upwards of 1.67 terabytes of data, including unreleased screenshots and concept art of the then-upcoming game Marvel's Wolverine, a timeline of upcoming Insomniac releases, as well as HR documents, emails, tax forms, internal conversations, and passports relating to current and former Insomniac employees, with the group posting a selection of this data as evidence of the theft. The group claimed it only took them 20-25 minutes to access the company's domain server and their motive was to publicly hold the stolen data for ransom. They offered to auction it off to anyone for 50 bitcoin, or $2 million USD, so long as the data was not resold by the new owners, with the deadline being a week from then. Reportedly 2% of the stolen data was purchased by unknown parties, but Insomniac did not purchase any of it back, leading Rhysida to release the remainder of the stolen data to the public.