In the 2017 Halloween DLC, the costumes for Phase 4, Honoka, and Marie Rose are ballerina outfits that are references to the ballet Swan Lake. Honoka is based on the protagonist, Odette; Phase 4 is based on the antagonist, Rothbart; Marie is based on the rival, Odile.

In the Japanese version of the game, Honoka and Marie's tag intro shows Honoka requesting to borrow Marie Rose's chest. This is meant to be a pun on both of their different bust sizes and a common Japanese phrase for requesting a sparring partner, believing power is derived from the chest. This interaction was changed in the Western versions to Honoka plainly asking for a practice round.

By February 21th 2018, Dead or Alive 5 Last Round's total price (DLC included) is that of $1,117.34, making it the most expensive fighting game in existence.

As part of a collaboration between Marvelous Interactive and Tecmo Koei, one of the DLC costume sets includes 16 outfits based on characters from the Senran Kagura series.

Exclusively in the Playstation 4 and Xbox One versions, the outfits can be destroyed as the characters take damage, just as they do in the Senran Kagura games.