In an interview with TechRaptor, lead developer Ryan Koons stated that the decision to make HuniePop a gameplay-centric title instead of a story-centric one like other dating sims didn't happen until months into development. The original intention was to make a traditional dating sim, only for Koons – who already had little interest in storytelling in video games – to overhaul the concept due to his growing ennui.

In the same interview, Koons stated that he deliberately sought to avoid many of the cliches associated with dating sims, particularly "the usual innocent waifu style character types." Consequently, the game's cast are based on people from his own life, and the writing is much more irreverent than other dating sims. In particular, Koons described deuteragonist Kyu Sugardust as a raunchy fictionalization of her voice actress, Jaclyn Aimee.