If the player does The Sad Seer quest after finishing the main quest, Oddfrid White-Lip will predict the player's future. She will say, through her friend Geilir the Mumbling, "When the dragon dies, the Empire dies. Where is the lost dragon's blood, the Empire's sire? And from the womb of the void, who shall stem the blood tide?"

This is actually a teaser to the plot of the fourth game in the Elder Scrolls series, Oblivion, which was unreleased at the time. The dragon is a reference to the Septim family line. During Oblivion, the supposed last Septim emperor dies, causing the Gates of Oblivion to open and the empire to fall into chaos. It is up to the player to find the emperor's missing heir, "the lost dragon's blood," and close the "womb of the void".

The remainder of this prophecy was revealed in a series of splash screens at the countdown to the Oblivion launch on the Official Elder Scrolls site:

When the dragon dies, the Empire dies.
Where is the lost dragon's blood, the Empire's sire?
And from the womb of the void, who shall stem the blood tide?
So long as the Blood of the Dragon Prince runs strong in her rulers, the glory of the Empire shall extend in unbroken years.
His heart's blood bleeds in darkness
For once the portals are opened, who shall shut them upon the rising tide?
For Lord Dagon forever reborn in blood and fire from the waters of Oblivion.
Find him... and close shut the marble jaws of Oblivion.

This prophecy expands upon the plot that would eventually be revealed in "Oblivion".