"Destroy All Humans!" was conceived of by then video game programmer Matt Harding, allegedly from a sarcastic remark he made following Microsoft's rejection of a family-friendly game concept, since he "didn't want to spend two years of [his] life writing a game about killing everyone". Harding later quit from Pandemic Studios and began compiling footage from an Asian walkabout vacation he had done, leading to the creation of the "Where the Hell is Matt?" videos. While he was not involved with the development of "Destroy All Humans!", he was given a conceptual credit.
Contributed by OtakuSoze