Though Tam Tam does not return as a playable character, the game's code still contains his character data, suggesting that he was going to be in the game in an early stage of development. However, any attempts to access the data will result in the game crashing.

Nicotine Caffeine's name originated from Adachi's addiction to coffee and cigarettes during the game's development.

"I came up with the name "Nicotine Caffeine" because I was addicted to coffee and cigarettes when we were developing the game. I took the words "caffeine" and "nicotine" and changed them to kanji characters. I no longer smoke cigarettes."

In the Devil's Island - Dinner battle stage, there is a large cauldron in the background being tended to by two creatures that resemble Gen-An Shiranui as they appear to be boiling three human heads and a Xenomorph from the Alien franchise in a vat of blood.

Ryuhaku Todoh from Art of Fighting makes a cameo appearance in Gen-An's ending as one of his opponents.

The Korean version of Samurai Shodown II has several differences compared to the other versions:
• Attract mode is completely silent. There are no music or sound effects regardless of the settings in the options menu.
• All blood is recolored to white.
• There are no in-game fatalities, though the referees still take away the opponent's corpse after the match ends.
• The background on the title screen is completely different.