Mass Effect was banned in Singapore due to a scene where it's possible for Female Shepard to have sex with the Female Asari Sha'ira. The ban was later lifted, however it was given an "M18" classification, making it the first video game in Singapore to ever receive a rating.

Note: According to the Galactic Codex: Essentials Edition 2183, while Asari have only one gender, they are not asexual like single-celled life; all Asari are sexually female.