Scrapped character ideas included Silver Surfer (his fighting style — energy blasts & zooming around on his board—didn't mesh well with a fighting game system), Dr. Strange (too similar to Dr. Doom), Mr. Fantastic (his stretching abilities were too hard to draw into sprite form), Daredevil (not compelling as a fighter), Black Widow (Same reason as Daredevil), Hawkeye (Not enough abilities for a moveset) and Scarlet Witch (too overpowered). Dr. Strange, Black Widow and Hawkeye eventually made their way into later games in the series.

Dan Habiki can have an alternate match intro if the player holds the light punch input during the match start screen which features Dan landing on the floor on his back and losing his sandals.

Sakura has an alternate win pose that can be initiated by holding down both kick inputs during a finishing super. After this is done one of Sakura's friends will join her for a dance together at the win screen.

If the player has enough meter then they can have Jill preform two Supers consecutively. If this is done a certain way and timed well while the Tyrant is on the level, she will fire a rocket launcher at it and the opponent it is attacking, Spoiler:making it look like the ending to Resident Evil (1996) where Jill does the same thing to the Tyrant to defeat it.

In the home console release, the clock in the Clock Tower stage is linked to the console's own internal clock and therefore shows the actual real-world time during matches.

According to the game's director Tatsuya Nakae in a 2000 Arcadia magazine #3 developer interview, he was asked if he could comment about the three new original characters: SonSon, Amingo and Ruby Heart in the game. Nakae stated that until now, Norimaro had been the only original character in Marvel vs. Capcom series, so he wanted to add more new characters in the game from the start. When Nakae asked the game's lead character designer Katsuhiro Eguchi for some designs, Eguchi told Nakae that he wanted to revive someone from a classic game and sent him a design that reinterpreted SonSon as a girl; Nakae stated "it was interesting and had a lot of impact" and put the character in the game.

Nakae then stated that Amingo was designed to fulfill the missing role of a non-human Capcom character that was "capable of really crazy movements", and that Ruby Heart was designed to be the leading character of the three newcomers (in a marquee role similar to Ryu and Cyclops) and as a new challenge to create a "cool, female character", the kind of which had not commonly taken center stage in games released at the time.

According to game's director Tatsuya Nakae in a 2000 Arcadia magazine #3 developer interview, he was asked how they were able to realize the support for the game's online matching service network (established in collaboration with Japanese telecom KDDI). He responded:

According to the game's director Tatsuya Nakae in a 2000 Arcadia magazine #3 developer interview, he was asked why the team included two Wolverines in the game, one with bone claws and the other with adamantium claws. He commented that the team wanted to focus on the bone claw Wolverine, but the directive from Marvel was that both had to be included in the game. This made it difficult for the team to differentiate the two characters as they look almost identical, so they had to think of where and how to add pronounced, yet subtle differences.

According to game's director Tatsuya Nakae in a 2000 Arcadia magazine #3 developer interview, he was asked how Cable and Marrow were selected for this game? He responded:

According to the game's producer Yoshihiro Sudo in a 2000 Arcadia magazine #3 developer interview, he acknowledged that the line charge for the arcade release of the game in Japan charging 13 yen per minute, meaning 50-60 yen per game, was a controversially high rate that the developers did not want to increase and that fans complained about for being too high, but that it was the lowest possible price they could charge the game at for the time being. He then expressed hope that the cost would lower as more people played the game.

When Jill Valentine removes her beret, it is shown that she has long hair tied in a ponytail underneath her beret to appear short.

This is inconsistent with the in-game portrayal and artwork of Jill in Resident Evil 1 (which her appearance is based off of), where she just has short hair. However, it does falls in line with the live-action portrayal of Jill in Resident Evil 1, as the actress who portrayed her also had short hair tied in a ponytail under the beret.

Ruby Heart was going to get her own game in 2014 for mobile phones called Dai Koukai Frontier ("Great Voyage Frontier"), but the game has been indefinitely postponed.

In the Japanese version of the game "Air Combos" are referred to as "Aerial Raves". There is a sound file in the international versions of the game of the announcer saying "Aerial Rave!", which goes unused due to the change.

The Japanese Dreamcast version of the game featured an online mode, allowing players to fight each other via the Dreamcast's modem or broadband adapter. This mode was removed from the international release for unknown reasons, with the game's logo taking it's place on the menu. The music associated with the mode is still in the files of the PAL and US release, but goes unused.

The character of SonSon is in fact the granddaughter of the protagonist from Capcom's Arcade game, SonSon.

If you kill the final character of a team with Dan's Premium Sign attack as it's thrown, it will count as a Hyper Combo Finish.

According to Yoshinori Ono, the character Ruby Heart started out as a character of the Darkstalkers series before being rejected and moved over to Marvel vs Capcom.