The player can completely softlock their game if an extremely complex and absurd series of actions are undertaken, forcing them to have no other choice but to start a new game. Specifically, if this is done, then the player will be stuck at either the Pokémon League building, Pacifidlog Town, Dewford Town, or Sootopolis City with only an Electrode that only knows the move Selfdestruct.

This is not possible in the Generation VI remakes.
Contributed by PirateGoofy
Video