The N64 Controller that was released for Nintendo Switch Online's Expansion Pack can be used on any Switch game. However, it lacks X and Y buttons leading to some games being partially unplayable when someone attempts to play them with one.

A Nintendo Switch actually helped to solve a murder investigation. On November 20, 2019, Matthew Wiser, a professor at the University of South Alabama, was shot and lost his life while his house was being burgled. One of the Items Stolen was Wiser's Switch. Authorities were able to track down the console's unique online signature when one of the perpetrators signed on to it long after the tragic theft had taken place, leading to investigators identifying Tiquez Timmons as one of the men involved in the incident. Timmons then implicated Derric Scott as the one who shot Prof. Wiser and burgled his house, while Timmons drove the getaway vehicle. This unique digital piece of evidence was actually used in court and helped to successfully convict the two young men of the crime.

Within 10 months after its release, the Nintendo Switch sold more units than the Wii U sold during its entire life span. By comparison, the Switch sold 14.86 million units in the first 10 months of its release on March 3, 2017, while the Wii U sold only 12.5 million units from its launch on November 18, 2012 until it was discontinued on January 31, 2017.

On July 17th, 2019, as part of a promotion with Nintendo, Southwest Airlines gave everyone on a flight heading to San Diego for San Diego Comic-Con a free Nintendo Switch bundled together with Super Mario Maker 2.

As of the 4.0.0 Update, which originally brought USB headphone support to the Switch, it was discovered that, via the use of the Wii U's Gamecube Controller Adapter, that almost every Switch game can be played with a Gamecube Controller. However, since the Gamecube Controller lacks a left Z-button the player does not have access to all of the controls of games that normally would utilize the Switch's ZL button.

The phrase "thx2allgamefans!" can be found written on the Switch Pro Controller's motherboard, just above the right analog stick; the positioning of this message allows it to be easily viewed by holding the right analog stick in the down position and peering through the surrounding socket.

The first batch of Nintendo Switch consoles suffered an issue where the left Joy-Con would frequently desync as the result of a manufacturing error. This could be remedied by placing a small square of conductive foam atop the Joy-Con's antenna traces, which would significantly reduce interference. Nintendo themselves would amend the desyncing issue in later batches of the Switch.

To avoid anyone from possibly swallowing Nintendo Switch game cartridges, Nintendo had them laced with Denatonium Benzoate, a non-toxic bittering agent, so they would taste horrible. The agent is also known to be used in animal repellent, nail-biting prevention, shampoos and soaps.

In the system's Photo Album set-up page, one of the drawn characters closely resembles the character 'GO' from the Japanese gay pornographic movie A Midsummer Night’s Lewd Dream. The film's character had become part of a popular meme in Japan which had spawned as a result of the film's over-the-top acting.