It's possible to play Japanese-region Nintendo 64 games on a U.S. Nintendo 64 console by replacing the cartridge's back panel with a back panel of any U.S. region Nintendo 64 game to bypass the region-locking tabs found within the system's cartridge slot.

The Nintendo 64 controller has the same color scheme as the Super Famicom Controller

Netscape's founder, Marc Andreessen, proposed to Nintendo to create an online service for the Nintendo 64, however Nintendo wanted full control and the deal fell through.

The Nintendo 64 was originally called the Ultra 64, as a tribute to several toys they manufactured in the late 1960's such as the Ultra Hand. However, Konami still held a trademark on the name "Ultra Games", and Nintendo was forced to change the name and logo for their new console.

Nintendo removed the Nintendo 64's ability to use RGB output (SCART/Component), but earlier versions of the console still have the ability to do so. An RGB signal can be achieved on the N64 by simply jumping a few wires on the motherboard and adding a few more electronic components.

64DD is a disc drive add-on for the Nintendo 64 that was announced on the Shoshinkai game show (Space world today) in Japan, talked about by Shigeru Miyamoto and released in Japan in 1999. It was never available outside of Japan.

Due to South Korea banning Japanese cultural imports at the end of World War II, the Nintendo 64 was distributed by South Korean company Hyundai, and was named the Comboy 64.